Mechanisms of action of Sappan lignum for prostate cancer treatment: network pharmacology, molecular docking and experimental validation

BackgroundProstate cancer (PCa) is the most common non-cutaneous malignancy in men globally.Sappan lignum, which exists in the heartwood of Caesalpinia sappan L., has antitumor effects; however, its exact mechanism of action remains unclear.This study elucidated the underlying mechanisms of Sappan lignum in PCa through network pharmacology approach

read more